This invention introduces a novel treatment for melasma, a skin condition characterized by dark patches on the skin. Traditional treatments for melasma often result in partial improvement and are plagued by recurring symptoms when treatment ceases. The new treatment combines a pharmaceutical composition of tranexamic acid, hydroquinone, arbutin, and a concentrated extract from the brown seaweed Ascophyllum nodosum with a CO2 laser featuring a cold pulse. This combination delivers significant improvements without the recurrence of melasma, achieving up to 98% reduction in dark spots. Additionally, this approach eliminates the common rebound effect seen with current treatments. Within weeks, patients observe substantial skin clearing, offering a psychological boost and higher satisfaction. This method provides a promising, less invasive solution, enhancing current dermatological practices.
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Melasma Treatment
Health & Safety
WO/2025/222267