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Targeted Cancer Treatment with Nanocarriers

Health & Safety
WO/2025/193917

Problem Solved

Current cancer treatments often struggle with targeting specific cancer cells without harming healthy cells. Traditional therapies can lead to significant side effects and are not always effective in suppressing cancer cell growth, migration, or invasion.

Core Features

This invention introduces a method using nanocarriers to deliver targeted treatments to cancer cells. These nanocarriers are designed to suppress genes involved in the Wnt/β-catenin signaling pathway, which is crucial in cancer cell proliferation and survival. The nanocarriers can be of three types: one with an antibody, one with siRNA, and one with both, all attached to nanoparticles.

Inventive Step

The novel aspect of this invention lies in its use of nanocarriers that combine antibodies and siRNA to specifically target and suppress genes in cancer cells. This dual-targeting approach allows for precise delivery and action within the cells, reducing the likelihood of affecting healthy cells and minimizing side effects.

Benefits

The invention offers a targeted approach to cancer treatment, potentially reducing side effects and improving the effectiveness of therapies. It can suppress cancer cell proliferation, migration, invasion, and even drug resistance, providing a comprehensive strategy against cancer.

Broader Impact

This technology could revolutionize cancer treatment by providing a more efficient and safer alternative to conventional therapies. It may lead to advancements in personalized medicine, improving patient outcomes and reducing healthcare costs.